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Tapotoclax also known as AMG 176 is an orally available small molecule MCL1 myeloid cell leukemia1 protein inhibitor being developed by Amgen for the No development reported Haematological malignancies Multiple myeloma NonHodgkins lymphoma
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News for tapotoclax AMG 176 Amgen BeiGene Tapotoclax Demonstrates Safety Yields AntiLeukemic Effects but No Responses in MDS Following HMAs OncLive Treatment with tapotoclax AMG 176 was tolerable and led to reductions in bone marrow blasts and transfusion dependence in patients with highrisk myelodysplastic syndromes MDS after hypomethylating agents HMAs according to data
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